Phage Therapy: Concept to Cure
نویسندگان
چکیده
منابع مشابه
Phage Therapy: Concept to Cure
The development and mass-production of antibiotics ranks as one of the twentieth century’s greatest scientific achievements. For more than 60 years, antibiotics have comprised Western medicine’s primary defense against bacterial disease. But although antibiotics have saved millions of lives, our chemical shield has become increasingly leaky. Just last year, the director-general of the World Hea...
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We modify existing models of bacteriophage growth on an exponentially growing bacterial population by including (1) density dependent phage attack rates and (2) loss to phage due to adsorption to both infected and uninfected bacteria. The effects of these modifications on key pharmacokinetic parameters associated with phage therapy are examined. More general phage growth models are explored whi...
متن کاملPhage therapy
Bacteriophage therapy, the use of viruses that infect bacteria as antimicrobials, has been championed as a promising alternative to conventional antibiotics. Although in the laboratory bacterial resistance against phages arises rapidly, resistance so far has been an only minor problem for the effectiveness of phage therapy. Resistance to antibiotics, however, has become a major issue after deca...
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According to WHO survey in 2010 there are 34 million people who are infected with HIV and attained AIDS. Per year about 1.8 million people dies with AIDS and 2.7 million new people become infected with HIV. AIDS is a secondary immunodeficiency caused by HIV virus that belongs to retroviral family. During AIDS T-cell count in blood falls tremendously below 200 cells ìl ̄ that results to be fatal ...
متن کاملRegulating phage therapy
I n a note published in The Lancet in December 1915, Frederic Twort described the discovery of an infectious, filterable agent that causes the glassy transformation and eventual killing of bacteria, now identified as Staphylococcus hyicus [1]. Two years later, Félix d’Herelle independently described an invisible microbe antagonistic to dysentery bacilli in a note to the Comptes Rendus de l’Acad...
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ژورنال
عنوان ژورنال: Frontiers in Microbiology
سال: 2012
ISSN: 1664-302X
DOI: 10.3389/fmicb.2012.00238